Objectives To explore the level of resilience among adolescents with Type 1 diabetes and its association with glycemic control,diabetes distress,and quality of life. Methods A total of 360 adolescents with Type 1 diabetes were recruited from the outpatient and inpatient in Endocrinology departments of 2 public hospitals in Nanjing by convenience sampling method. The data were collected by the Diabetes Strengths and Resilience Measure for Adolescents,the Problem Areas in Diabetes Scale-5,the Short Form of the Chinese version Diabetes Quality of Life for Youth Scale,and the Self-Designed General Information Questionnaire. Results The resilience of adolescents with Type 1 diabetes was 40.18±9.27,which was above the medium level. Resilience was negatively correlated with glycosylated hemoglobin value（r=-0.373,P<0.001） and diabetes distress（r=-0.336,P<0.001）,while it was positively correlated with quality of life（r=0.431,P<0.001）. Hierarchical regression analysis showed that resilience independently explained 10.0% of the variation in glycemic control,7.8% of diabetes distress,and 17.7% of the quality of life,after controlling for demographic and disease variables. Conclusions Interventions that target patients’ resilience may improve their glycemic control,mental health,and quality of life,which should arouse the attention of medical workers.